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Understanding Our Body's Pain Management Mechanisms

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Chapter 1: The Power of Our Mind in Pain Management

In this continuation of my earlier discussion on reducing pain without medication, I aim to clarify why certain methods work (or sometimes don't) for alleviating pain. This information is intended to assist you, Jenny Lane, and anyone else who may find it useful.

General Structure of the Article

  1. Why do non-pharmaceutical methods alleviate pain?
  2. Why might non-pharmaceutical methods fail to alleviate pain?

Section 1.1: Understanding Pain

Pain isn't merely a straightforward "bottom-up" phenomenon. In other words, it’s not simply the case that activating one nerve cell equates to feeling a unit of pain. For instance, ten stimulated nerve cells do not necessarily translate to ten separate sensations of pain.

While pain often arises from an identifiable physical injury, it also has a significant "top-down" component. This means that our perception of pain can be influenced by cognitive and psychological factors. Our thoughts and experiences can alter our body's responses to injuries or pain-inducing stimuli.

These cognitive processes can be shaped by various factors, including the techniques discussed in my previous article: placebos, social learning, support from others, expectations, and verbal guidance.

Why does this happen?

One of the primary reasons lies in the fact that our body produces its own pain-relieving substances. We generate endogenous opioids, which are internal compounds that help manage pain. When opioids are synthesized externally and ingested, they are termed exogenous opioids. While these substances effectively reduce pain, there are times when our bodies may not produce sufficient amounts to cope with severe pain, signaling to our brain that additional support is needed.

Thus, anything that promotes the release of our own opioids can contribute to pain relief. Activities that elevate our mood and stimulate opioid release—like exercising, enjoying a good movie, listening to music, socializing, indulging in favorite foods, attending concerts, or even riding roller coasters—can all be beneficial.

Optimally, we should focus on enhancing our body's natural production of endogenous opioids, as this can lead to a more sustainable approach to pain management.

An interesting note: placebos, which also stimulate opioid release, tend to be more effective in individuals who are empathetic, optimistic, easily hypnotized, attentive to bodily sensations, neurotic, and altruistic.

Section 1.2: The Limitations of Non-Pharmaceutical Pain Relief

Despite the benefits, there are inherent challenges and complexities in this approach. The human experience is multifaceted. Just as one stimulated nerve does not equate to one sensation of pain, the production of one endogenous opioid does not guarantee a proportional reduction in pain.

When attempting to employ certain techniques or thoughts to alleviate pain, we may encounter conflicting feelings. Even well-intentioned efforts can sometimes backfire if we aren’t cautious.

Consider this scenario:

You’ve just read about various methods to manage pain without relying on medication and are eager to give them a try. You share your newfound excitement with friends and encourage yourself to explore these techniques. However, after trying a few methods, you find little to no relief, leading you to dwell on your pain.

As days pass and your attempts yield no results, frustration builds. You might wonder, “Didn’t the author suggest that a change in mindset and the support of friends could help?”

Indeed, I did. However, the more we focus on trying to alleviate pain, the more attention we inadvertently draw to it, potentially exacerbating our discomfort. This mental preoccupation can diminish the effectiveness of our body's natural opioids.

As motivation wanes, the temptation to resort to medication becomes stronger. It’s true that sometimes medication may be necessary, but stressing over our health can often do more harm than good.

This cycle can lead to feelings of guilt—"Why is this so hard? Why can’t I stick to my plan?"—which can intensify pain. We must learn to accept our pain rather than resist it. Ignoring it or forcing it down can reinforce its presence and diminish our confidence in managing it.

Furthermore, conflicting advice from friends can complicate matters. With so many differing opinions, it’s easy to feel lost and question whether anyone truly understands your situation.

Navigating these challenges can be difficult, but recognizing them is the first step toward moving past them and regaining a sense of optimism.

Chapter 2: Finding Your Path to Healing

Ultimately, while it may be easier said than done, embracing these concepts can lead to a more manageable way of life. With time, you may wonder how you ever approached pain differently.

Until next time.

-Alex

References:

Colloca, L., & Grillon, C. (2014). Understanding placebo and nocebo responses for pain management. Current pain and headache reports, 18(6), 1–7.

Colloca, L. (2019). The placebo effect in pain therapies. Annual review of pharmacology and toxicology, 59, 191.

Devan, H., Hale, L., Hempel, D., Saipe, B., & Perry, M. A. (2018). What works and does not work in a self-management intervention for people with chronic pain? Qualitative systematic review and meta-synthesis. Physical therapy, 98(5), 381–397.

Miller-Matero, L. R., et al. (2021). A brief psychological intervention for chronic pain in primary care: A pilot randomized controlled trial. Pain Medicine, 22(7), 1603–1611.

Ask Alex Anything!

Feel free to ask questions! I've addressed various topics related to motivation and well-being.

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